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The Natural and Expansive Applications of Human Chorionic Gonadotropin

Human chorionic gonadotropin (HCG) is an embryonic hormone that stimulates the release of progesterone to sustain pregnancy. It consists of 237 amino acids having a molecular mass of 25.7kD.

Clinically, HCG is used to treat ovarian disorders and stimulate ovulation in women. In men, it is used to induce testosterone production in patients who are not capable of making testosteronein normal levels. In young boys, HCG is utilized to stimulate the testicle to descend to the scrotum when it has failed to do so by natural means.

1hcgdropsHuman chorionic gonadotropin (HCG) and the other glycoprotein hormones, namely, luteinizing hormone(LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH),are heterodimers that share a common alpha subunit and possess distinct beta units that are unique to their G protein-linked receptors.As a substance, Human Chorionic Gonadotropin (HCG) is analogous to Luteinizing Hormone(LH). The chemical similarity of hCG to LH results in similar action mechanism in males. Both HCG and LH attach to receptors on human Leydig cells, aprocess that triggers the production and secretion of testosterone.

The parallelism drawn between HCG and LH has made HCG a popular adjunct to performance-enhancing anabolic androgenic steroids (AAS). Injection or introduction of AAS places the body on anegative-feedback mode. Natural regulatory mechanisms respond by shutting down the hypothalamic-pituitary-gonadal axis (HPGA) which leads to stoppage of testosterone production. Testicular deterioration in size and normal functions, among other abnormalities, is one of the side effects of HPGA shutdown.

Elevated quantities of anabolic androgen steroids prompt the hypothalamus to cease producing gonadotropin-releasing hormone (GnRH). In the absence of GnRH, the pituitary gland is unable to release luteinizing hormone (LH). Under ordinary circumstances, the LH would have been released from the pituitary gland to the testes through the bloodstream to trigger the production and secretion of testosterone.The absence of LH prevents the testes from producing testosterone.

HCG is commonly utilized to perform LH functions of prompting normal testosterone production and release as well as maintaining and restoring testicular size during and after steroid cycles. Its association with the use of AAS placed hCG on the list of illicit drugs in several sports. Athletes found guilty of using HCG were suspended or banned temporarily.

Prolonged and excessive dosage that results toelevations intestosterone amounts beyond natural levels would ultimately restrain its own production through negative body feedback mechanisms on the pituitary gland and on the hypothalamus.Should this happen, hCG would have lost its functionality as a substitute for LH.

Among its proponents, there are ongoingdiscussions on what is the optimum frequency in using hCG alongside AAS cycles to ensure maximum benefits. When used in moderation, HCG assists in maintaining normal testicular condition and size.However, it is also speculated that the sporadic use of hCGallows the testicles to remain responsive to LH when the user goes off a steroid cycle.

This may be attributed to HCG’s ability to keep or defenda certain level of Inter-Testicular-Testosterone (ITT) when taken within the cycle. This could help hasten recovery of the hypothalamic-testicular-pituitary-axis. If taken after a cycle, it could still play a part in restoringtesticles back to their normal size and in providing stimulation for the Leydig cells. Other analysts have suggested blending the two schemes of hCG administration in a training regimen.

Side effects of using HCG alone are very rare and hardly serious.Gynecomastia,the development of abnormally large breasts in males, can occur due to heightened levels of the estrogen hormone but it is, nonetheless, uncommon.Combined with anabolic androgenic steroids, hCGhas been known to cause depression, headaches, and edema.

HCG is an embryonic hormone that stimulates the release of progesterone to sustain pregnancy, more details are given at

Garden City Homes for Sale—Tips for Buying a House

One of the major purchases that you would ever have in your life is buying your very own house. People dream about having their own house and when you are close to realizing this dream for yourself, you have to be 100% sure about your decision.

If you are planning to buy a house in Garden City or in any other place, it is also important that you learn some useful tips that will help make the whole process easier. Remember that buying a house is not the same as buying clothes or even cars. This is a much more expensive purchase and it requires much thought and preparation. Click here to give you some useful tips for buying Garden City homes for sale, you need to review the following paragraphs.

Improve your credit rating

Real estateOne of the first things that you need to do is to strengthen your credit. Unless you are paying for the house in full amount in cash, you have to apply for a housing loan offered by banks and other lending institutions. You can strengthen your credit by paying your bills on time or paying off all your debts. Get a copy of your credit report to ensure that all the details and information are correct.

Consider the kind of house that you want to buy

The kind of house that you should buy largely depends on the people who will live in it. If you do not have a family yet but are planning to have in the future, you should consider buying a house that has a nice neighborhood where your kids can grow up. It should also be big enough for an average family. You need to consider the same things if you already have a family of your own. If you are planning to live by yourself and want to live in a house big enough for only one person, you should consider buying a small condo unit.

Consider your budget

It is also important to consider how much you can afford and how much you are willing to spend when buying your house. You have to remember all the expenses that go with buying and living in your own house such as down payment, equity, mortgage, real estate taxes, agent’ fees, and so on. It is especially important to consider the mortgage that you need to pay every month once your loan is approved.

Find a real estate agent who can help you

Real estate agents can provide you with a list of Garden City homes for sale that suit your needs and budget. He can help you get your housing loan approved by giving you professional advice and tips. Your real estate agent will also explain to you everything that you need to know about buying a house, something that all house buyers, especially first time buyers, need.

Do you lose things? Get ID lanyards

Some people are predisposed to lose things. This is just an unlucky characteristic that some people have. It may be forgetfulness, and it may not be at all. The fact is that these people just tend to have the bad luck to lose random items at different times. This, of course, is a costly thing when it comes to important items. If you want to avoid a couple of these problems and are one of these people, you can solve it with something called ID lanyards.

ID lanyards by wholesalelanyards are a keychain made to be worn around the neck. At the end of it, keys can be attached, and an ID can be stored in the card holder. The fabric of the lanyard is long enough that the keys and ID sit very comfortably on the chest at all times. These accessories are affordable and can be purchased nearly anywhere. Your local drug store or gas station may even carry several styles of them to choose from so you can find the right color or pattern to suit your tastes.

wholesalelanyardsThe benefit for people that lose things is obvious. People that lose things run the risk of a very expensive and unfortunate problem if they lose their keys or their ID. It will not only cost them a significant amount of money, but will also make them have to do without these items for a while as new ones are being made. In addition, changing locks will cost a bunch of money and take a long time. This is never a good thing for someone who has this problem. And a person that is pre-disposed to do this often will have to encounter this at least a couple times in their life, which is even more of an unfortunate situation for them.

ID lanyards help to decrease the risk of this happening. When the ID card and the keys are worn around the neck comfortably, the individual can determine where exactly they are at all times. If they do not feel them there, they may have put them somewhere. This makes them very easy to find if they are lost, solving the problem of the chunk of time and money that have to be dispensed to fix this problem. Knowing where your ID and keys are at all times is helpful for someone that loses these items.

As an added benefit, the keys and ID card sit comfortably around the neck, so no comfort is sacrificed in order to make sure the important items do not get lost. This means that they can be worn all day without the desire to take them off. That way, the individual will be able to keep their keys and ID on them no matter where they are during their day.

If you are one of the people that tends to lose things, you know how much of a troublesome condition this can be – not to mention expensive and time-consuming at times. Losing important items such as your keys and wallet on a regular basis can be incredibly expensive and time-consuming, not to mention the chunk it will take out of your life. If you want to solve this problem, or at least decrease your risk of losing these items, the ID lanyard is the perfect item for you. Your keys will be kept around your neck so that you will be able to tell where they are at all times. This is a great solution for a problem that some people have. Now, if that ID lanyard could only find the remote control.

Inspecting your Storage Container

Storage containers provide buyers and renters with a variety of options in securing cargo for transport or temporary storage. For the first-timers, looking for just even a decent container may be complicated by the fact that most companies today offer tempting deals and seemingly innovative features to their storage containers.

The greatest tip out there perhaps is simple: stick to the basics first. Furnishings such as additional locks, sophisticated ventilation systems and some high-tech security features are only as good as the basic features that your new storage container has. Here are some things that you need to look for when searching for storage containers:

Storage containersSurface rust – Since most cargo containers up for grabs have been used in the past, surface rust will almost always be present. Surface rust is, of course not apparent for repainted containers. If you don’t have a choice but to go for a slightly rusty container, be sure to haggle and try to get it at a lower price as much as possible.

One thing to remember about surface rust is that it is particularly critical if it is found on the door area and the bottom part. The door area has hinges and made up of component, soldered parts. No matter how strong the steel body of the container is, this part will always be the weakest link in the steel structure of the container.

Also, during inspection, be sure to look at the bottom part of the container by asking it to be turned so that you can see that part clearly. Presence of rust in this area should make you think twice about getting that container since the bottom part is important in providing support for the cargo (especially during transit and loading via cranes.)

A sign of deep rust in the steel structure of a container is the presence of pin-sized holes. These holes are very difficult to spot with the naked eye. A nice trick is to go inside the container in broad daylight and close it. (Make sure someone is outside just in case you get locked inside.) Supposed to be, the interior will be pitch black (which indicates an intact steel structure). Perforations will manifest as small holes where light can pass through.

Door – Old containers don’t just suffer from rust, they also suffer from corrosion. The first sign that corrosion has already started is a container door that is misaligned. Swing doors repeatedly and be keen for any signs of misalignment. The door gaskets (the rubber linings along the door edges) must also be inspected. It should not be rotten nor missing. Gaskets provide a watertight seal around a door and obviously, broken and missing gaskets compromise the water-proofing ability of storage containers.

Read! – Refrain from buying storage containers without any intact CSC (Container Safety Convention) plate. This plate contains information regarding when the container was manufactured. Even the history of maintenance can also be seen in this plate. By taking time to read this plate, you will be able to discern the age of the container as well as the maintenance history by the time you are renting it or buying it.

Of course, in terms of pricing, the age of the container is not really a critical factor when compared to the actual physical state of the container but this gives you a rough idea on its supposed state. If you will use your container for human habitation, CDC plates will also give you information regarding the pesticides and other chemicals used to treat the wooden floorings.

This will give you an idea about the treatments needed to neutralize and seal-off these toxic chemicals (different pesticides and chemicals need specific chemical treatments).


Author Bio:

Moveable Cubicle storage containers and come with high security lock boxes for additional safety of your goods, merchandise, furniture, equipment and almost everything you may want to store.

Working at Home: Making a DIY Printed Circuit Board

Printed circuit boards are everywhere. They can be found on a smartphone a businessman uses, the computer that a call center agent works on, or on a tablet that a kid uses to play games. These devices work efficiently due to the support of PCBs. They can be readily bought in stores or can be ordered online; but for those who need a printed circuit board but has no budget to buy it, and resourceful and patient enough to create it, this can also be made at home using cheap materials.

For a DIY printed circuit board, the materials to work with are: a copper-clad board, a glossy photo paper, a solution of ferric chloride, a small-hole drill, acetone, clothes iron, a tape, a cutter or a hacksaw blade, a marker, and water. Get more about DIY printed circuit board from

The first step is designing the desired pattern for the PCB. This can be done by drawing on the glossy photo paper. But to be more accurate, it is recommended to use computer software that enables to check the exact spots for fitting the components later. It will also ease the modification jobs and can be printed directly.

PcbnetThe next process will be printing the circuit design. There are many methods to do this like photo transfer, milling, or direct transfer. However, the easiest way for a homemade PCB is the toner transfer method. This is through the use of a glossy photo paper and a laser jet printer. The design’s image is printed on the paper and has to be cut out.

Take the copper-clad board, which will serve as the actual circuit. Precisely cut it out the same size of the paper. This can be done by using a sharp cutter for small-sized boards or a hacksaw blade for the larger ones. To ensure that the board is clean from any dirt, grease, or fingerprints, acetone is wiped through it. If there is no acetone present, then rubbing a metallic sponge until the board becomes shiny is beneficial; but take note that this is a time-consuming process.

The fourth step is attaching the design’s image to the copper-clad board. Tape the cut-out image; make sure that it faces down. Press the clothes’ iron onto it, which is set at the highest temperature within a period of five minutes. This is to melt the toner and the plastic, making it stick onto the board.

The next step is peeling off the paper from the board. Soak the entire board into a cup or basin of water, preferably boiling in about 25 minutes. This can separate the paper from the copper-clad board. The remaining paper remnants can also be manually peeled off. Take note that some parts of the print may be removed a bit, but you need not worry because it can be traced back using a permanent marker.

The board can now be etched. During this process, you need a ferric chloride solution. For those who are unfamiliar about what ferric chloride is, it is an orange-black, sometimes brown solid solution which is slightly soluble in liquid. It has the ability to corrode or dissolve most of the metals, including copper. Submerging the board on the solution while stirring it in for about 10 minutes will remove the excess copper parts that were uncovered by the toner; but when using it, make sure to wear protective coverings such as gloves and masks.

After doing so, wipe away the toner with acetone or by simply dipping it again on a basin of water and scrubbing again with a metallic sponge. Now the copper pattern will be easily recognized.

The next step is drilling the holes for the circuit components using a small drill. Make sure that when drilling, no other surfaces will be damaged. Now the circuit components, as well as the wiring, can be attached. This will mark the completion of the homemade printing circuit board.

Making a DIY printed circuit board is very useful aside from being fun. Having a handmade PCB will also increase your knowledge about electrical circuits and other related components.

Strategic Talent Management

Investing in people is a huge necessity in any working organization. Good talent management means good working output, which equally spells success for the company. This is a process to which an individual’s skills are developed to provide more efficient service to a company. Developing people from the inside of the organization is like developing one’s own army to battle. People are trained and their skills are honed so they can perform at their maximum working potentials and be an asset to company. How the staff members are trained and improve rests on the hands of the human resources team. The functions of the HR arm of an organization are hugely significant to the overall performance of the company.

In talent management, it is important to take look into what the future might hold, or what the business may need in the coming years. Planning ahead can save tremendous amounts of time, money, and effort. The process of managing talent starts by identifying the image of the company that should be shown to the recruits. It is important to choose the identity of a company in accordance with the corporate strategy. Stating this at the beginning of the process will provide huge amounts of savings because the human resources personal’s effort is focused on a single or a specific idea.

Talent managementAdapting the goals and objectives of the company is the best way of immersing hired personnel into the workforce. By using a corporate identity, the company is introduced and made known to the employees. The core values and beliefs of the organization should be transferred and passed down to the new recruits, instilling commitment in their ends. On the other hand, part of strategic human management is knowing what keeps the employees come back to work each day. Also, the HR personnel should know what drives the people to strive harder. These details can be used when creating a development scheme for the employees.

The selection process is also not a walk in the park. Based on a set of criteria or competencies set by the human resources team, decisions regarding the selection and recruitment are made. These criteria include different aspects including the previous work experiences, analytical ability, and ability to blend with the workplace. Managing the performance of an individual requires the feedback of the coaches or supervisors in addition to the different evaluation tools that may be used to assess the individual. Competencies are the basis by which a candidate can be hired or not. Specific competencies are required in the recruitment process to thoroughly evaluate the people that may be valuable for the company.

Another area that is covered under talent management is the compensation method, including the rewards and benefits provided by the company. Some organization may not be enthusiastic in giving out rewards, but providing these positive reinforcement is a way to motivate the employee to do better at their work. One of the primary reasons why people stay in a company is to satisfy the personal financial needs. Sometimes people seek for satisfaction with regard to the workplace, or satisfaction in the job. Others seek for lifestyle stability, and some others for continuous learning and growth. Improper compensation may lead to loss of human capital.

In addition, talent management may also include the development of leadership and managerial skills. These skills are proven handy in a working environment, for example in decision making situations or in daily organizational tasks. Recruits of today are best honed to be leaders of tomorrow. These people with high potentials need an effective training ground to be able to develop their skills.

Author Bio:

TalentKeepers' award-winning learning modules engage learners in a variety of learning techniques including simulations, quizzes, tips, and best practices to increase knowledge and skills.